SDS FinderConcentration Calculator
Name
Syringic acid
CAS
530-57-4
Synonyms
3,5-Dimethoxy-4-hydroxybenzoate
3,5-Dimethoxy-4-hydroxybenzoic acid
3,5-Dimethoxybenzoyl hydrazine
3,5-Dimethyl-4-hydroxybenzoate
3,5-Dimethyl-4-hydroxybenzoic acid
4-Hydroxy-3,5-dimethylbenzoate
4-Hydroxy-3,5-dimethylbenzoic acid
Cedar acid
Syringate
Syringlicacid
Molecular formula
C9H10O5
Average molecular weight
198.17
Monoisotopic mass of parent ion
198.0528
Verified Purity
98%
Solubility
N/A
Spectra
Chromatogram
N/A

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mg
g/mol
mM

Find the weight

mM
g/mol
mL

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g/mol
mL
mg
g/mol
(%)
Chloroform
100
80
60
40
20
0
0
20
40
60
80
100
MeOH
(%)
(%)
H2O
100
80
60
40
20
0
0
20
40
60
80
100
MeOH
(%)
(%)
H2O
100
80
60
40
20
0
0
20
40
60
80
100
DMSO
(%)
H2O (pH)
9
8
7
6
5
4
3

Information

Version
5.0
Status
Detected but not Quantified
HMDB Name
Syringic acid
SMILES
COC1=CC(=CC(OC)=C1O)C(O)=O
Description
Syringic acid, also known as syringate or cedar acid, belongs to the class of organic compounds known as gallic acid and derivatives. Gallic acid and derivatives are compounds containing a 3,4,5-trihydroxybenzoic acid moiety. Outside of the human body, Syringic acid is found, on average, in the highest concentration within a few different foods, such as common walnuts, swiss chards, and olives and in a lower concentration in apples, tarragons, and peanuts. Syringic acid has also been detected, but not quantified in several different foods, such as sweet marjorams, silver lindens, bulgurs, annual wild rices, and barley. This could make syringic acid a potential biomarker for the consumption of these foods. Syringic acid is correlated with high antioxidant activity and inhibition of LDL oxidation. Research suggests that phenolics from wine may play a positive role against oxidation of low-density lipoprotein (LDL), which is a key step in the development of atherosclerosis. Syringic acid is a phenol present in some distilled alcohol beverages. It is also a product of microbial (gut) metabolism of anthocyanins and other polyphenols that have been consumed (in fruits and alcoholic beverages - PMID:18767860). Syringic acid is also a microbial metabolite that can be found in Bifidobacterium (PMID:24958563).

Physical Properties

State
Solid

Experimental Properties

Property
Value
Reference
Melting Point
206 - 209 °C
Boiling Point
440.00 °C. @ 760.00 mm Hg
The Good Scents Company Information System
Water Solubility
5783.0 mg/L @ 25 °C (est)
The Good Scents Company Information System
LogP
1.04
HANSCH,C ET AL. (1995)

Biological Properties

Cellular Locations
N/A
Biospecimen Locations
Blood
Feces
Saliva
Urine
Tissue Locations
N/A

Normal Concentrations

Biospecimen
Status
Value
Age
Sex
Condition
Reference
Details
Blood
Expected but not Quantified
Normal
Blood
Detected and Quantified
0.0-7.1 uM
Adult (>18 years old)
Male
Normal
Blood
Detected but not Quantified
Adult (>18 years old)
Both
Normal
Feces
Detected and Quantified
2.119 nmol/g wet feces
Adult (>18 years old)
Both
Normal
Feces
Detected and Quantified
3.885 +/- 1.867 nmol/g wet feces
Adult (>18 years old)
Both
Normal
Feces
Detected and Quantified
9.285 +/- 5.601 nmol/g wet feces
Adult (>18 years old)
Both
Normal
Feces
Detected but not Quantified
Adult (>18 years old)
Both
Normal
Feces
Detected but not Quantified
Adult (>18 years old)
Both
Normal
Feces
Detected and Quantified
2.155 (0.121-6.0704) nmol/g wet feces
Adult (>18 years old)
Both
Normal
Feces
Detected but not Quantified
Adult (>18 years old)
Both
Normal
Saliva
Detected and Quantified
1.57 +/- 0.123 uM
Adult (>18 years old)
Both
Normal
Saliva
Detected and Quantified
1.59 +/- 0.118 uM
Adult (>18 years old)
Not Specified
Normal
Saliva
Detected and Quantified
1.62 +/- 0.105 uM
Adult (>18 years old)
Both
Normal
Saliva
Detected and Quantified
1.71 +/- 0.0913 uM
Adult (>18 years old)
Male
Normal
Urine
Expected but not Quantified
Consuming polyphenols described by Phenol-Explorer entry 420
Urine
Detected and Quantified
1.5 umol/mmol creatinine
Adult (>18 years old)
Both
Normal
Urine
Detected and Quantified
0.9 +/- 0.2 umol/mmol creatinine
Adult (>18 years old)
Not Specified
Normal
Urine
Detected but not Quantified
Adult (>18 years old)
Both
Normal

Abnormal Concentrations

Biospecimen
Status
Value
Age
Sex
Condition
Reference
Details
Feces
Detected but not Quantified
Adult (>18 years old)
Both
Colorectal cancer
Urine
Detected but not Quantified
Adult (>18 years old)
Both
Hypertension (mild)
Urine
Detected but not Quantified
Adult (>18 years old)
Both
Hypertension (mild)

Spectra

Type
Description
View
Predicted GC-MS
splash10-0f8a-0900000000-7b568e18ffde6ab04131
Predicted GC-MS
splash10-00fr-8095000000-575a6ec78ed017731cc6
Predicted GC-MS
Predicted LC-MS/MS
splash10-0002-0900000000-6ce63e339a947f904864
Predicted LC-MS/MS
splash10-001j-0900000000-a397243a2d8f8f9e501d
Predicted LC-MS/MS
splash10-001r-2900000000-d3241b91846d43efb768
Predicted LC-MS/MS
splash10-0002-0900000000-e699dd409e203e12842f
Predicted LC-MS/MS
splash10-0uds-0900000000-b5bde1ce65999b3cf7de
Predicted LC-MS/MS
splash10-0fa9-2900000000-87c04717df825474388d

Pathways

Name
SMPDB / Pathwhiz
KEGG
None available